Paolo Nutini began singing at a young age, encouraged by his grandfather and his teacher at school. His fondness for music reached such heights that he dropped out of school and began working as a roadie and selling t–shirts for Speedway. He learned the skills of performing live and the business surrounding music for three years. As a part of this venture, he worked at the Park Lane Studio in Glasgow Park. At the start of 2003, David Sneddon was to perform in Paisley at a concert organized by 102.5 Clyde 1. But after Sneddon was delayed, Nutini got a chance to perform live and the crowd’s response kicked off his career.
Brendan Moon became Paolo Nutini’s manager, followed by a move to London to perform at venues such as Balham's The Bedford. He also played live music at the Hard Rock Café and Radio London, as well as supported the likes of KT Tunstall, Amy Winehouse and The Rolling Stones. At some concerts, he used to sing with his eyes closed and that became a distinctive feature about him. By 2006, he was playing to sold–out crowds across the UK and had even gone on to play at the Carnegie Hall in New York City, festivals such as Oxegen, T in the Park and the Wireless Festival. He also appeared live on Later with Jools Holland, a famous UK TV show. During this time, he supported the Rolling Stones twice and also played at The Austin City Limits Music Festival in Texas.
In 2007, Paolo Nutini played at the Ahmet Ertegun Tribute Concert, alongside the likes of Led Zeppelin, who were playing for the first time in twenty seven years. By then, his songs were making waves all over in the US, featured on such TV shows as Scrubs, Gavin & Stacey, One Tree Hill, Grey's Anatomy, CSI Miami, CSI: NY, The Jane Austen Book Club and more. He also played live on The Tonight Show with Jay Leno and in 2008; he contributed in the music of Ecstasy, a movie based on Irvine Welsh's novel of the same name. He also collaborated with many artists, appearing on The View's 2009 album.
In 2009, Paolo Nutini came out with his second album, which debuted at Number One on the music charts. It also spawned a number of successful singles, which climbed up the UK Singles Chart. Over in the US, he performed one of his songs on the Conan O'Brien show with the album gaining fame all over the US. It was praised by the likes of Allmusic, who called it a mix of American and Scottish pop and folk music. The Independent, similarly, praised the album as one that saw him make “giant strides in several directions” and went so far as to say that “don’t be surprised if, come December, this is one of the year's biggest–selling albums.”
The Daily Telegraph also praised the album, stating that it “organically blends soul, country, folk and the brash, horny energy of ragtime swing.” The likes of The Guardian and The Observer also covered the album, which ranked on the UK Albums Chart at Number One position with more than sixty thousand copies sold shortly after. It also debuted second on the Irish Albums Chart and became the Best–Selling UK Albums of the year. It also led to his winning the Meteor Award for the ‘Best International Album’. The album was followed up by a world tour that saw dates in many parts of the world.
Nutini, who has performed at the London 2012 Olympic Games Opening Ceremony, can be heard sing live, after purchasing Paolo Nutini tickets at his many American concerts.